Tianeptine is particularly known to be an antidepressant treating depression of different causes and nature. It was found to be highly effective either for both: minor mood disorders or for serious major and latent depressions, and also obsessive-compulsive disorders and social anxiety.
There is some evidence that Tianeptine can be helpful in dealing with neurodegenerative disorders like Alzheimer’s disease, cerebral aging, or multiple sclerosis.
Tianeptine is a drug that is included as a main active substance in a number of medical drugs essentially composed of Tianeptine: [Stablon, Coaxil, and Tatinol].
This drug is widely used for clarity of thoughts, lucid mind, relieving a feeling of sadness, and enhancing overall mental performance: memory, learning, comprehension of abstract thinking.
Among derivate effects of its main prescription, Tianeptine also provides useful benefits like reducing anxiety, mood booster, etc.
Even considering that this drug was developed in the early 1960s, unlike all other nootropics of this period, Tianeptine has a neuroprotective mechanism allowing it to be more safe and reliable.
Chemically Tianeptine contains three rings of atoms in its structure.
This structure enables Tianeptine to enhance re-uptake and reabsorption of the brain neurotransmitter – Serotonin.
Selective Serotonin reuptake enhancer/inhibitor (SSRE or SSRI) within the brain.
This means that this nootropic prevents Serotonin from being destroyed by enzymes after it was released. Tianeptine allows to reuptake Serotonin by neurons increasing the effectiveness of their function.
Such an action mechanism gives your brain more fuel by normalizing a balance between neurons’ action and metabolic activity within the brain.
And, on the other hand, decreased Serotonin activity in the pre-frontal cortex, improving your mood.
Also, Tianeptine has a remarkable action not only on Serotonin.
It also increases concentrations of Dopamine – a neurotransmitter responsible for your good mood, feeling of pleasure, excitement, sex drive, and many other emotional responses, along with Glutamate receptors which play a role in improving cognitive functions such as learning, and memory.
Glutamate also plays an important role in synaptic plasticity (or neuroplasticity) and modulates AMPA, NMDA, and metabolic glutamate receptors within the brain.
These are used for the vast majority of processes related to excitation and sending electrical responses to areas responsible for cognitive functions.
There is also one substantial benefit of Tianeptine which is worth to be mentioned.
This nootropic is deemed to be safe not only for its neuroprotective ability but also because it’s well-tolerated by elders.
Even with a poor history of studies and trials, this smart drug was found to be effective for many users who appreciated its benefits.
There is a number of reviewers‘ comments and topics about the positive effects of Tianeptine.
Among all positive effects declared in studies and clinical trials, users report on some of the benefits found to occur at most.
And according to blog posts and comments, Tianeptine is used for treating depression where the majority of reviews confirm its excellent anti-depressant potential.
The second popular benefit of Tianeptine is its ability to improve memory functions and overall cognitive performance.
Though Tianeptine is reported to produce likely positive effects, there are still reports on a poor result of using Tianeptine or no effects at all.
Tianeptine had earned a reputation as a safe drug with strong antidepressant effects, and normally all medical specialists suggest consulting with a therapist before starting with this drug due to the possible side effects.
Users should be aware of possible contraindications when Tianeptine is being taken with other medications. And especially if a user receives complex and toxic medications.
It’s important to be informed about the side effects of any supplement you are about to take together with Tianeptine as some of them may produce serious outcomes which may aggravate the state of your health.
As for Tianeptine, this drug is reported to cause different side effects but in most cases, these side effects are mild and do not trouble much.
These include some minor changes in sleep pattern (vivid dreams) and more heavy like insomnia, dry mouth, constipation, dizziness, drowsiness, low blood pressure.
In fact, these side effects only bring discomfort rather than any health risks.
Tianeptine Sulfate Dosage
Normally, it’s required to take about 25-40 mg of Tianeptine per day.
But this dosage may differ since this nootropic helps from different types of mental disorders and of course, the dosage for minor depression and Alzheimer’s disease or obsessive-compulsive disorders will not be the same.
A general recommendation for every new user is to carefully listen to your body and start with small doses of this drug.
A small dose, in this case, would be either one pill per day cut in half.
Even considering that side effects of Tianeptine are rare to occur and very unusual, nevertheless for the sake of safety, you should always consult with your therapist before starting Tianeptine for better dosage determination.