The Best Nootropics You Can Get In 2021

best nootropics

Today the best nootropics or “smart drugs” (drugs, dietary supplements, or herbal extracts that enhance brain function or/and protect the brain from neurodegenerative disease) become more and more popular.

According to a study, a fifth of leading university students in the UK has taken prescription drugs such as Modafinil to improve memory and learning abilities.

But the term “nootropic” is too broad and blanket and doesn’t give any clear information on the effectiveness and real value of a drug.

Nowadays there are literally tons of brand names available on the market that can easily misguide you in your efforts to find the best solution for your needs.

Even spending a tremendous amount of time browsing the internet, reading research papers and studies might not provide you with the most up-to-date information on the most effective smart drugs.

Besides, the best nootropics vary in their effectiveness.

Nootropics Effectiveness

Some have delicate and cumulative effects. And you have to go through a full course to feel any positive results.

Some provide acute effects right after intake.

For instance, some nootropics such as Noopept or Bacopa which boost brain-derived neurotrophic factors require a number of weeks so you could benefit from their effects.

It means that you won’t feel any immediate cognitive enhancement, but taking these neuropeptides periodically will more likely affect your neuroplasticity and even neurogenesis.

So, in some cases, you shouldn’t expect to feel any immediate brain boost effect. But it doesn’t mean that a drug doesn’t work!

The chart below is based on the data (surveys, polls, sentiment analysis of users’ feedback) gathered from different social media platforms such as Reddit, Twitter, Longecity, etc.

And its intent is to give you a quick overview of the most performing smart drugs for today.


As you can see people give their credits mostly to stimulant drugs such as Modafinil, Adrafinil, Armodafinil.

The last two are analogs of Modafinil and share the same mechanism of action.

Apart from Modafinil or Modafinil-like stimulants, users also vote for phenylpiracetam (Phenotropil), caffeine, nicotine, coluracetam, and Noopept.

Phenylpiracetam and Coluracetam are members of the racetam family of drugs.

Both drugs demonstrate good potential for cognitive enhancement, increasing memory and concentration.

And both are being tested for treating a variety of neurological disorders such as Alzheimer’s disease.

According to recent studies, phenylpiracetam demonstrates an ability to restore cognition after a stroke.

Also, it was found to be effective in the complex therapy of patients suffering from epilepsy.

Coluracetam is a fairly new nootropic and although there are just a few studies on its efficiency, it looks promising for people willing to improve their memory or protect the brain from neurological degeneration.

Another popular nootropic among the internet community is Noopept.

Interestingly, Noopept was produced in Russia, but it is sold as a dietary supplement in the US.

There are many exciting studies on the neuroprotective properties of Noopept.

This fact also helps this smart drug to stand out in a crowd and gain such popularity among users.

I think it’s important to note that herbal supplements such as Ginkgo Biloba, DMAE, and Ginseng have been poorly rated by users.

It might seem a little confusing, considering that Ginkgo demonstrates relatively strong evidence for its nootropic effects.

But apparently, stimulant drugs expose much stronger effects for most users’ needs.

But it doesn’t mean that herbal supplements don’t work and can not be effective in your particular case.

In my experience, Ginkgo Biloba has great potential and could be very effective when it comes to vascular disorders.

It helped me to get rid of a few very unpleasant symptoms associated with hypertension and problems with my blood vessels.

I should admit that it didn’t make me super focused or significantly improve my memory or cognition.

But it helped me a lot with feeling less tired during the day and vastly reduced my tension headaches.

So it’s always important to clearly understand what drug you’re about to take and the reason why you need it.

There is no magic pill that will solve all of your problems overnight, but there are definitely a lot of nootropic compounds that can make your life much easier if assigned and administered properly.

Best Amino Acids And Natural Organics

Another category of popular nootropics is amino acids and natural substances.

In fact, one of the best-selling categories of dietary supplements is amino acids.

In most cases, amino acids are a popular topic among the bodybuilding community.

But in fact, amino acids such as Creatine or L-Theanine can be beneficial for nootropic purposes.

Creatine is a nitrogenous organic acid that is responsible for recycling cellular energy (ATP).

Indeed, this substance (when used as a supplement) is popular mostly within the bodybuilding community.

But studies show its efficacy for brain performance and energy and even for slowing Parkinson’s disease.

L-Theanine has also gained popularity among the best nootropics for its ability to reduce anxiety and stress.

Being a natural anti-stress agent L-Theanine is able to boost GABA and other brain calming chemicals.

But not only does it increase the level of GABA, but it also facilitates an increase of serotonin and dopamine in the brain.

Also, L-Theanine enhances alpha brain waves which produce an effect of so-called  “wakeful relaxation”. The effect is when you’re relaxed, but not sleepy.

The real power of L-Theanine comes when it’s taken along with caffeine. Such a combination might improve cognition and perform as a mood booster.

Wrapping Up

Despite a wide range of opinions about the effectiveness of contemporary “smart drugs”.

It’s reasonable to highlight the three most trending categories of modern nootropics appreciated by the majority of users online.

Top Stimulant Drugs

Top Racetam Drugs

Noopept is a peptide-derived compound and is pretty much closely related to the racetam family. But to be precise it’s not a racetam nootropic in a full meaning of the term.

Top Amino Acids

It’s always up to you which nootropic to choose.

But you should keep in mind that it’s always essential to ask your doctor whether a drug is good for you or not prior to its usage.

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